Use in homicide
In 2006, Petr Zelenka, a assistant in the Czech Republic, advisedly administered ample doses to patients, killing 7, and attempting to annihilate 10 others.60
editOverdose issues
In 2007, a assistant at Cedars-Sinai Medical Center afield gave amateur Dennis Quaid's twelve-day-old twins a dosage of heparin that was 1,000 times the recommended dosage for infants.61 The balance allegedly arose because the labeling and architecture of the developed and baby versions of the artefact were similar. The Quaid ancestors afterwards sued the manufacturer, Baxter Healthcare Corp.,6263 and acclimatized with the hospital for $750,000.64 Prior to the Quaid accident, six bairn babies at Methodist Hospital in Indianapolis, Indiana were accustomed an overdose. Three of the babies died afterwards the mistake.65
In July 2008, addition set of twins built-in at Christus Spohn Hospital South, a hospital amid in Corpus Christi, Texas, died afterwards an accidentally administered balance of the drug. The balance was due to a bond absurdity at the hospital pharmacy and was different to the product's packaging or labeling.66 As of July 2008, the exact could cause of the twins' afterlife was beneath investigation.6768
In March 2010, a two year old displace accommodating from Texas was accustomed a baleful dosage of heparin at the University of Nebraska Medical Center. The exact affairs surrounding her afterlife are still beneath investigation.69In December 2007, the U.S. Food and Biologic Administration (FDA) recalled a addition of heparin because of bacterial advance (Serratia marcescens) in several unopened syringes of this product. The bacillus Serratia marcescens can advance to life-threatening injuries and/or death.56
Main article: 2008 Chinese heparin contamination
In March 2008, above recalls of heparin were appear by the FDA due to contagion of the raw heparin banal alien from China.5758 According to the FDA, the adulterated heparin dead 81 humans in the United States. The admixture was articular as an "over-sulphated" acquired of chondroitin sulfate, a accepted shellfish-derived supplement generally acclimated for arthritis, which was advised to acting for absolute heparin in authority tests
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